The cause of virilizing adrenal hyperplasia is :
a. Defect in cortisol synthesis
b. defect in ACTH synthesis
c. Defect in testosterone synthesis
d. All of the above
e. None of the above
Isha@2663 Answered question August 14, 2024
a. Defect in cortisol synthesis
Virilizing adrenal hyperplasia is often caused by a defect in cortisol synthesis, typically due to a deficiency in the enzyme 21-hydroxylase. This defect leads to an accumulation of adrenal androgens, resulting in symptoms of virilization.
Isha@2663 Answered question August 14, 2024