Regarding the cellular mechanisms of vascular leakage, which of the following is
INCORRECT
A. the ‘immediate transient response’ only occurs in venules of 20-60 µm diameter.
B. sunburn can cause a delayed and prolonged vascular leakage.
C. the endothelial injury caused by leukocytes is due to free radical-induced damage.
D. the cytoskeletal and junctional retraction mechanism is mediated by the complement
system.
E. the most common mechanism for increased vascular permeability is “endothelial
contraction” (“immediate transient response”)
D. the cytoskeletal and junctional retraction mechanism is mediated by the complement system is incorrect. Cytoskeletal and junctional retraction is primarily mediated by mechanisms involving histamine, bradykinin, or leukocyte-derived mediators, not the complement system.