Regarding granulomatous inflammation, one of the following is INCORRECT.
A. central caseous necrosis is rare in all granulomatous diseases EXCEPT tuberculosis.
B. both Langerhan’s and foreign-body type giant cells may be seen in the granulomas of sarcoidosis.
C. acid fast bacilli are seen in leprosy and tuberculosis
D. fungal infections cannot result in granulomas.
E. the “gumma” is the granulomatous manifestation of syphilis
The correct answer is D. fungal infections cannot result in granulomas.
Fungal infections can indeed result in granulomas. Many fungal infections, such as histoplasmosis, cryptococcosis, and coccidioidomycosis, can trigger a granulomatous response. Granulomas are a common histopathological feature of many fungal infections.
