What is the primary pathophysiological mechanism in immune thrombocytopenic purpura (ITP)?
- A) Bone marrow suppression
- B) Increased platelet destruction
- C) Decreased platelet production
- D) Vitamin K deficiency
aanya.bansal Answered question August 31, 2024
The correct answer is B) Increased platelet destruction.
Immune thrombocytopenic purpura (ITP) is an autoimmune disorder characterized by:
– Increased destruction of platelets by the immune system
– Production of anti-platelet antibodies that bind to platelets, marking them for destruction
– Removal of antibody-bound platelets by the spleen and other reticuloendothelial tissues
aanya.bansal Answered question August 31, 2024