How do serological tests help in monitoring the progression of chronic infections?

Serological tests play a crucial role in monitoring the progression of chronic infections by:

1. Tracking antibody levels: Measuring changes in antibody titers over time helps assess the immune response and infection progression.

2. Detecting seroconversion: Identifying a change from negative to positive antibody status indicates recent infection or reactivation.

3. Monitoring antibody avidity: Measuring the binding strength of antibodies helps determine the maturity of the immune response.

4. Identifying antigenic shifts: Detecting changes in antigenic profiles helps monitor virus mutation or strain variation.

5. Assessing treatment response: Serological tests evaluate the effectiveness of treatment by monitoring changes in antibody levels or antigen presence.