A hydrophilic medicinal agent has the following property:
a) Low ability to penetrate through the cell membrane lipids
b) Penetrate through membranes by means of endocytosis
c) Easy permeation through the blood-brain barrier
d) High reabsorption in renal tubules
a) Low ability to penetrate through the cell membrane lipids. Hydrophilic agents struggle to cross lipid membranes due to their water-attracting nature, making them less permeable through cell membranes.
The correct answer is:
a) Low ability to penetrate through the cell membrane lipids
Hydrophilic (water-loving) medicinal agents have a low ability to penetrate through cell membrane lipids, which are hydrophobic (water-fearing). This is because hydrophilic substances are not soluble in lipids and therefore have difficulty crossing the cell membrane.