A 25 years old healthy woman has delivered a baby who after birth, is drowsy and found to have a cerebral hemorrhage. Her platelet count is 21000/mm3 and the maternal platelet count is 1,30,000/mm3. Maternal serum will most likely show:
a. Antibodies to HIV
b. Anti HPA-1a antibodies
c. Platelet auto antibodies
d. Anti HLA antibodies
Pramiti Kumari Answered question August 24, 2024
The most likely finding in the maternal serum in this case is b. Anti HPA-1a antibodies. The baby’s low platelet count and cerebral hemorrhage suggest that the mother may have alloimmune thrombocytopenia due to the presence of anti-HPA-1a antibodies, which are associated with neonatal alloimmune thrombocytopenia (NAIT).
Pramiti Kumari Answered question August 24, 2024