Which of the following is a diagnostic feature of Hodgkin lymphoma?
- A) Bence Jones proteinuria
- B) Reed-Sternberg cells
- C) Rouleaux formation
- D) Philadelphia chromosome
aanya.bansal Answered question August 31, 2024
“Reed-Sternberg cells” is the correct answer.
Reed-Sternberg cells are a distinctive type of abnormal lymphocyte that is characteristic of Hodgkin lymphoma. They are large, abnormal cells with a distinctive appearance under the microscope, featuring:
– A large nucleus with a prominent nucleolus
– A distinctive “owl’s eye” or “mirror-image” appearance
– Expression of CD30 and CD15 surface markers
aanya.bansal Answered question August 31, 2024