What is the purpose of using control samples in serological assays?

Control samples are used in serological assays to:

1. Validate test performance: Ensure the test is working correctly and producing accurate results.

2. Detect cross-reactivity: Identify non-specific binding or false positives.

3. Determine specificity and sensitivity: Establish the test’s ability to distinguish between positive and negative samples.

4. Standardize results: Compare results to a known standard, ensuring consistency.

5. Monitor test variability: Detect changes in test performance over time.

6. Verify reagent quality: Ensure reagents are functioning properly.

7. Troubleshoot issues: Identify and resolve technical problems.