D –ve HUS is due to the inherited deficiency of:
a. Factor I and H
b. Complement C3, C4
c. ADAMTS 13
d. Large vWF multimers
Isha@2663 Answered question August 16, 2024
A. Factor I and H
D+ve HUS (Hemolytic Uremic Syndrome) is typically associated with inherited deficiencies of complement regulatory proteins, specifically factor H and factor I. These deficiencies lead to uncontrolled complement activation, which is a key feature of the disease.
Isha@2663 Answered question August 16, 2024