Which of the following changes is associated with irreversible cell damage?
A. glycogen depletion
B. flocculent densities in mitochondria
C. cellular swelling.
D. loss of microvilli.
E. detachment of ribosomes from rER.
The correct answer is B. flocculent densities in mitochondria.
Flocculent densities in mitochondria are a characteristic feature of irreversible cell damage. They represent areas of mitochondrial matrix densification, indicating severe mitochondrial injury and dysfunction.
The other options are associated with reversible cell damage:
A. Glycogen depletion: Cells can replenish glycogen stores once the stress is removed.