Complement is involved in the pathogenesis of each of the following EXCEPT

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129 viewsAugust 17, 2024Pathologypathogenesis pathology

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facetiuskyle 51 July 21, 2021 0 Comments

Complement is involved in the pathogenesis of each of the following EXCEPT
A. Arthus reaction.
B. contact dermatitis.
C. erythroblastosis foetalis.
D. haemolytic transfusion ABO reaction.
E. serum sickness.

Isha@2663 Answered question August 17, 2024

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score 0 · Answer 1 · 2024-08-17T16:30:34+00:00

B. contact dermatitis.

Contact dermatitis is primarily a type IV hypersensitivity reaction mediated by T cells, rather than complement. The other conditions listed—Arthus reaction (type III hypersensitivity), erythroblastosis fetalis (type II hypersensitivity), hemolytic transfusion reaction (type II hypersensitivity), and serum sickness (type III hypersensitivity)—involve complement activation.