Downs Syndrome is NOT associated with:
A. transposition between chromosome 14 and 21 (t14:21)
B. Epicanthal fold and single palmar crease
C. Increased risk of Leukemia and Alzheimers disease
D. Radial aplasia
E. Trisomy 21 from maternal dysjunction
The correct answer is D. Radial aplasia.
Down syndrome is associated with:
– Trisomy 21 (an extra copy of chromosome 21)
– Translocation between chromosome 14 and 21 (t14:21) in some cases
– Epicanthal fold (skin fold at the inner corner of the eye) and single palmar crease (a single crease in the palm of the hand)
– Increased risk of:
– Leukemia (blood cancer)
– Alzheimer’s disease (neurodegenerative disorder)